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Semen Analysis

Semen analysis is a fundamental laboratory test used to assess male fertility by evaluating the quantity and quality of a man’s semen and sperm. It helps identify potential male factor infertility and is typically one of the first investigations in an infertility workup.

Purpose of Semen Analysis

Evaluate sperm production and function.
Detect abnormalities in sperm count, motility, morphology, or volume.
Help diagnose causes of male infertility (e.g., varicocele, obstruction).

Pre-Test Instructions

Abstinence period: 2–7 days before sample collection.
Collection method: Usually through masturbation into a sterile container.
Avoid: Lubricants or condoms unless specified (non-toxic collection condoms may be used).

Interpretation of Results

Low sperm count (oligozoospermia): May indicate hormonal issues, varicocele, infections, or lifestyle factors.
Low motility (asthenozoospermia): Affects the sperm’s ability to reach the egg.
Abnormal morphology (teratozoospermia): Poor shape can impair fertilization.
No sperm (azoospermia): May be due to obstructive or non-obstructive causes.
High white blood cells: Suggests possible infection or inflammation.

Additional Tests (if abnormalities are found)

Repeat semen analysis (at least two samples, 2–3 weeks apart).
Hormonal profile: FSH, LH, testosterone, prolactin.
Scrotal ultrasound (e.g., for varicocele).
Genetic testing (e.g., karyotyping, Y-chromosome microdeletions) in severe cases.
Sperm DNA fragmentation tests (in selected cases).