The Micro Test, also known as Microfluidic Sperm Sorting or Microfluidic Sperm Selection, is an advanced diagnostic tool used in fertility treatments to assess and select the best sperm for in vitro fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI). This technique is designed to improve sperm selection by using a microfluidic system that mimics natural conditions to help identify the most viable and motile sperm.
A semen sample is collected and prepared in the laboratory.
The sperm sample is passed through a microfluidic chip — a tiny, specialized device that uses small channels and fluid flow to filter and sort sperm based on their motility (movement), morphology (shape), and viability (ability to fertilize an egg).
The high-quality sperm are separated from poor-quality sperm and other debris (like dead sperm or immature sperm) through the microfluidic process.This mimics the natural selection process that occurs in the female reproductive tract, where only the healthiest sperm reach the egg.
The best sperm are then selected and injected into eggs using ICSI or used in an IVF cycle for fertilization.
Improved Sperm Selection: Unlike traditional sperm selection methods, which rely heavily on sperm motility or morphology alone, the Micro Test helps choose sperm with better chances of successful fertilization by simulating natural conditions.
Better IVF/ICSI Outcomes: By selecting high-quality sperm, the chances of fertilization success and embryo quality are enhanced.
Reduction of DNA Fragmentation: This method may help reduce the likelihood of selecting sperm with high DNA fragmentation, which can affect fertilization and embryo development.
Non-invasive and Efficient: The process is typically quick, and the technology is gentle on sperm, preserving their integrity for optimal use in fertility treatments.
Male infertility caused by low sperm count, poor sperm motility, or abnormal sperm morphology.
Recurrent IVF failure due to poor sperm quality.
High DNA fragmentation or poor sperm health as indicated by traditional sperm tests.
Assisted reproductive technologies (ART) like ICSI, where sperm quality is a significant factor in success.