Egg Donor - oocyte Donation IVF program Chennai, India

EGG DONOR

EGG DONOR OOCYTE DONATION

Egg donation is the process where a woman donates her eggs / oocytes to an other women for any use. The use is commonly for IVF / Research purposes.

Who is an Egg donor ?

Egg donor is the woman who donates her eggs to an other woman.

Donor Requirements
  • Between the ages of 18 and 30.
  • Physically and Mentally healthy
  • Have a BMI 19- 26
  • Non-Smoker / Non-Alcoholic
  • Have regular, monthly menstrual periods
  • Psychologically healthy
  • No history of drug / substance abuse
  • No family history of inheritable genetic disorders
  • Willing to take injections
  • Willing to travel daily and be admitted for day care procedure of egg retrieval.
  • Able to keep appointments
How's the chance of success with donor egg IVF ?

According to statistics from the Society for Assisted Reproductive Technology, the highest success rate country-wide for IVF comes from the use of fresh embryos from donor eggs. IVF transfers resulting in live births in women of all ages are: Fresh embryos from donor eggs – 54.9% Thawed embryos from donor eggs – 35.7% By comparison, fertility treatment using fresh embryos from non-donor eggs had a maximum success rate of 46.3% for transfers resulting in live births, but this applies only to women aged younger than 35 years. For older women, the success rate drops right down to 6.5% in women over 42 years.

Whats the cost of Egg Donor IVF ?

There are various ways of participating in Egg donor program. Our program caters to all classes of society. Kindly contact our team to know more details.

Can you select Donors ?

Donor selection process is according to ICMR rules of Indian Government.

Egg Donor Process

Once you decide to use donor eggs, the first step is to choose your donor. Our Fertility team will be able to help you find a suitable match. Your menstrual cycle is synchronized with that of the donor, who receives IVF stimulation until the eggs are ready to be retrieved. Meanwhile Fertility specialists will help to prepare you for receipt of the embryo and may prescribe hormone replacement therapy for you. Once the eggs are combined with sperm from your partner or sperm donor and an embryo forms, the transfer takes place in the same way as IVF with non-donor eggs.

  • Step 1 : Enrolment into the Egg donation program
  • Step 2 : Screening Donor Profiles / Egg donation Bank / Frozen Donor Eggs
  • Step 3 : Donor and Recipient Synchronisation
  • Step 4 : Donor Stimulation / Recipient Endometrial preparation
  • Step 5 : Donor Egg Freezing / Donor egg IVF / ICSI
  • Step 6 : Embryo transfer / Embryo Freezing
  • Step 7 : Post IVF Checkup for the Donor and Pregnancy Tests for the Recipient
Pros and Cons of IVF with Donor Eggs

    Most women prefer to try IVF treatment and Embryo transfer using their own eggs first, because they want their child to be a product of their own body. The main disadvantage of using donor eggs is that this is not possible as the gamete belongs to a third party. However, when compared with the options of adopting or remaining childless, egg donation provides hope and a strong chance of success. In addition, the high rate of pregnancies from IVF using donor eggs makes it a more certain and cost-effective process, particularly for older women / women with severe endometriosis / premature ovarian failure.

Fertility Treatments

IUI

IVF

EGG DONATION

AZOOSPERMIA

SURROGACY

Egg cell

There is no waiting list for Egg Donation Treatment, as donor availability is more than efficient.

Women interested in IVF or Egg Donation Treatment should be no more than 50 years old.

    We aim to pair the donors according to the recipients’ requirements. The main criteria for pairing are physical characteristics and criteria related to personality, education, lifestyle etc.

The average donor age at our clinic is 25.
According to Indian law (ICMR) , donors remain strictly anonymous. Recipients are allowed information regarding the donors’ characteristics, personality, education, lifestyle and medical test results. However, they are not allowed to see photos or in any way come in contact with the donors
An initial consultation is of crucial importance, as during that time we review your medical and fertility history, check all your tests results, perform necessary examinations and, of course, answer all your potential questions. Alternatively, particularly if you live abroad, we may arrange telephone discussions or regular e-mail contacts in order to minimize your visits to India.
Our travel assistant offers different levels of service available. We would recommend you to stay somewhere near the Centre, in order to cut down on cost and time of local transportation.
Patients having fertility treatment must have recent (within the last 6 months) results for Hepatitis B, C, HIV I, II, VDRL. You will be asked to sign the consent forms, which we provide you. Passports or identity cards and Medical visa are also required.
As mentioned above, we can arrange frequent telephone and email discussions and consultations in order to minimize travelling inconvenience.
Our Specialists will meet you at the consulting offices by appointment. Appointments can be arranged either via the coordinator or directly with one of the consultants.
We provide 8 eggs on average.
The number of embryos transferred, depends on the recipient’s reproductive history and age and on the quality of embryos themselves. We usually transfer 2 embryos but single embryo transfers are welcome.
The initial consultation will take about an hour or two. If you are travelling as a couple, you need to arrive in India the day before or on the day of egg collection at the latest as your partner will provide us with a semen sample on that day. You will need to stay until embryo transfer which usually takes place 2 to 4 days later. If embryo transfer is to be performed at blastocyst stage this takes place 5 or 6 days after egg collection. Alternatively your partner’s sperm may be frozen earlier and you would only need to be in India for the day of embryo transfer.
  • The aim of treatment is to time your cycle with that of the donor’s cycle by giving you tablets to prepare the lining of the uterus to receive embryos.
  • On the 2nd or 21 st day of your cycle preceding the cycle your donor is due to start treatment you should commence down regulation injections either.
  • Buserelin 0.5 ml subcutaneously once daily or Leuprolide 20 units subcutaneously once daily.
  • You will continue on this treatment until contacted.
  • Our IVF coordinator will confirm your availability for treatment and arrange with you the appropriate charges.
  • On the day when the donor is due to start her superovulation injections, you will have an ultrasound scan. You will start Progynova 2mg tablets to be taken one tablet three times daily. Follow up scans will be arranged according to your response and donor’s stimulation course. The dose of oestradiol tablets may be altered.
  • Your partner will be asked for a semen sample on the day of egg retrieval. The day prior to egg collection Increase oestradiol valerate2mg to 2 tablets three times daily (unless already on a higher dose).
  • Start progesterone Crinone vaginal gel once every evening Or Gestone 50mg injection, intramuscularly once daily. Start anti-clotting injections (Low Molecular Weight Heparin) either Clexane subcutaneously once daily.
  • On the day of the donor’s egg collection a semen sample is required from your partner, so it is essential that he should be available for this. Alternatively sperm may be frozen before treatment and stored until use.
  • On the day following egg collection the midwife coordinator will contact you and let you know how many embryos fertilized, arrange the date and time of embryo transfer and inform you about possible embryo freezing.
  • Embryo transfer is performed 2-3 days after egg collection or 5-6 days after egg collection (blastocyst stage). It is a simple, painless procedure almost like having a pap smear / speculum examination.
  • You need to attend with a full bladder, so you will be asked to drink 4-5 glasses of water an hour before your arranged appointment.
  • Following embryo transfer you will continue all your medications as described above. Twelve days after embryo transfer have a blood pregnancy test (‚-HCG).
  • If your test is positive you must continue your medications until the 12th week of pregnancy unless otherwise advised by your own doctor.
  • If the test is negative stop all medication and expect a menstrual bleed after a few days.
An IUI shouldn’t be done at home without medical supervision because the sperm needs to be washed to prevent infection — i.e., separated from the semen. A vaginal insemination can be done at home, but is no more successful than intercourse. Some doctors are willing to instruct on doing ICI (intracervical insemination) at home, but it should not be attempted without being taught proper technique. Getting semen or air into the uterus could be quite dangerous — perhaps life-threatening. One woman wrote in to say there is a midwife practice in Berkeley, CA, that will do inseminations at the patient’s home, so it may be worth asking about.
It doesn’t usually happen, but it isn’t uncommon. It is most common to have some bleeding if the doctor had trouble reaching the cervix. Some women also have light bleeding with ovulation.
Implantation generally takes place 6-12 days after ovulation — so 6-12 days after a well-timed IUI. See abstract.
This depends on the type of IUI Cycle. Natural cycle costs less. Stimulation cycle costs higher. Stimulation with gonadotropin injection is much costlier with much higher results. Cost of the IUI procedure is approx Rs.3500
This depends mostly on how the female is being treated. A natural cycle is often timed to over the counter ovulation prediction kits, which cost $15-60 for 5-9 tests. The use of clomiphene citrate can increase the monitoring, but many doctors don’t do ultrasounds or settle for one u/s around cycle day 12. Gonadotropins increase both medication costs and the necessity of ultrasounds and bloodwork.
Many doctors monitor follicle development during IUI cycles. Most trigger when the dominant follicle is within a certain size range. While there is always some difference in doctor preference, the norms are unmedicated 20-24mm, clomiphene citrate 20-24mm, FSH-only meds 17 or 18mm minimum, and FSH+LH would be 16 or 17mm minimum. It is possible for slightly smaller follicles, 14-15mm, to contain a viable egg. Also, follicles continue to grow until they release, usually at a rate of about 1-2 mm per day. A woman may ovulate more than one follicle in a cycle, but the releases will occur within 24 hours. When hCG is not used, only follicles close in size are likely to release. The use of hCG induces ovulation in about 95 percent of women, and will get most mature follicles to rupture.
The E2 level should be 200-600pg/ml per 18mm follicle. Some doctors are content with a minimum level of 150, but higher tends to be better.
The main risks are some discomfort such as cramping, minor injury to the cervix that leads to bleeding or spotting, or introduction of infection (including sexually transmitted disease from the sperm itself — it helps to be sure of the known donor’s health, or use carefully monitored frozen specimens). There are also risks of hyperstimulation associated with the use of ovulation induction medications such as clomiphene citrate (low risk) and gonadotropin therapy (higher risk). Proper technique and adequate monitoring reduce risks.
Most women don’t need medication for pain associated with IUI. If there is cramping, it is best to avoid medications such as ibuprofen and naproxen (NSAIDS), but Tylenol is considered safe (but maybe not that helpful for cramps).
It is sometimes also called sperm preparation or spinning. It is a laboratory technique for separating sperm from semen, and separating motile sperm from non-motile sperm, for use in assisted reproduction (IUI, IVF). The washing technique for near normal specimens is mixing the ejaculate after liquefaction with the appropriate washing medium followed by centrifugation. (A centrifuge is a machine that separates materials with different densities by spinning them at high speed.) The supernatant is discarded and the sediment (sperm rich fraction) is re-suspended in more washing medium. This process is repeated 2-3 times maximum. In the final wash, the sediment is re-suspended in 0.5 cc of medium, loaded into a syringe and deposited in the uterus. The “Sperm Rise” or “Swim-up” technique is one in which two to five cc of medium are carefully layered on top of 0.2-0.5 cc of semen. Motile sperm cells “swim-up” into the culture medium. After some time (30-90 minutes) the medium (containing motile sperm cells) is carefully harvested and centrifuged. If necessary, fresh medium is layered on top of the seminal fluid again to harvest more sperm cells. The discontinuous gradient centrifugation technique utilizes a dense liquid phase to separate sperm cells from seminal fluid and debris. There are different compounds commercially available that may be used. Semen is deposited on top of this fluid and subjected to centrifugation. Motile sperm cells migrate to the bottom of the tube, which are used for IUI after further washing.
No. A tubal ligation is effective birth control because it prevents the sperm and egg from meeting. The process that leads to pregnancy is having an egg released from a follicle in the ovary and then beginning the journey to the uterus through the fallopian tube. Sperm will travel from the vagina, through the cervix, through the uterus, into the tube where fertilization occurs. IUI bypasses the need for the sperm to travel through the cervix, but that’s it. It doesn’t get the egg to the other side of the obstruction, so fertilization won’t take place. The only way to get pregnant after tubal ligation is by having reversal surgery or an assisted reproduction technology that includes egg retrieval, such as in vitro fertilization (IVF).
No. A tubal ligation is effective birth control because it prevents the sperm and egg from meeting. The process that leads to pregnancy is having an egg released from a follicle in the ovary and then beginning the journey to the uterus through the fallopian tube. Sperm will travel from the vagina, through the cervix, through the uterus, into the tube where fertilization occurs. IUI bypasses the need for the sperm to travel through the cervix, but that’s it. It doesn’t get the egg to the other side of the obstruction, so fertilization won’t take place. The only way to get pregnant after tubal ligation is by having reversal surgery or an assisted reproduction technology that includes egg retrieval, such as in vitro fertilization (IVF).